Discussion
Diagnosis With Brief Discussion
- Diagnosis
- Miliary tuberculosis
- Radiologic Findings
- Fig 1. Chest PA shows numerous tiny nodules in both lung fields.
Fig 2-4 Chest CT scan shows numerous military nodules in both lungs.
Fig 5 Mediastinal setting chest CT scan shows enlarged right paratracheal lymphadenopathy
- Brief Review
- Miliary tuberculosis (TB) refers to clinical disease resulting from the hematogenous dissemination of Mycobacterium tuberculosis. Miliary TB can arise as a result of progressive primary infection or via reactivation of a latent focus with subsequent spread. The term miliary TB was originally a pathologic and then a radiographic description; it is now used more broadly (and incorrectly) by some to denote all forms of progressive, widely disseminated TB, whether or not disease presents with the classic radiographic or pathologic nodular appearance characteristic of hematogenous spread. Use of biologic agents such as tumor necrosis factor (TNF)-alpha inhibitors has been associated with a disproportionate increase in cases of extrapulmonary and miliary tuberculosis among individuals treated with these agents.
- References
- 1. Jeong YJ, Lee KS. Pulmonary tuberculosis: up-to-date imaging and management. AJR 2008; 191: 834-844.
2. Keane J, Gershon S, Wise RP et al. Tuberculosis associated with infliximab, a tumor necrosis factor alpha-neutralizing agent. N Eng J Med 2001; 345: 1098.
- Keywords
- Lung, Lymph node, Infection, Pulmonary tuberculosis,